系统医学大事记索引
系统医学/系统生物学大事记
发布: 2002.11.08
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    2002 年英国专家Denis Noble 在《科学Science》上发表的一篇综述。题目是心脏模型,从基因,细胞到整个心脏。他用心脏的研究进展举了一个系统生物学成因的例子。这篇文章给于什么是系统生物学的解释具有范例作用。英文的维基百科把Denis Noble列为系统生物学的主要权威人士之一。

Dr. Noble offers the 10 Principles of Systems Biology as part of its definition : 

  1. Biological functionality is multi-level
  2. Transmission of information is not one way
  3. DNA is not the sole transmitter of inheritance
  4. The theory of biological relativity: there is no privileged level of causality
  5. Gene ontology will fail without higher-level insight
  6. There is no genetic program
  7. There are no programs at any other level
  8. There are no programs in the brain
  9. The self is not an object
  10. There are many more to be discovered; a genuine ‘theory of biology’ does not yet exist